Pharmaceutical companies will increasingly apply the predictive modeling of quantitative pharmacology to do more efficient drug development, says Kathy Giacomini, PhD, co-chair of the Department of Bioengineering and Therapeutic Sciences (BTS), a joint department of the UCSF Schools of Pharmacy and Medicine, and its new Center for Quantitative Pharmacology.
Interviewed in the wake of the recent symposium launching the center, Giacomini notes that new drug candidates that work in vitro and in animal models are mostly failing in Phase 2 and 3 of clinical trials due to a lack of efficacy or safety issues. More: Kathy Giacomini cites increasing impact of quantitative pharmacology.
